The final question, then, when considering the object of knowledge, is whether the spatial-temporal universe exists by itself or whether we must presuppose the existence of God in order to think intelligently of the spatial-temporal world. We found that, according to Christian theism, every individual object of knowledge to be known at all must be known in its relation to God. Then if one spatial object is to be known in its relation to another spatial object, the connection must be thought of as made by God. In other words, the universals of knowledge have their source in God. Similarly, if one object of knowledge is to be known in its relation to other objects of knowledge that have existed or will exist at another period of time, we must think of the connection as being made by the plan of God.
– Cornelius Van Til, A Survey of Christian Epistemology p.183