Calvin makes a sharp distinction between the revelation of God to man and man’s response to that revelation. This implies the rejection of a natural theology such as Aquinas taught.
He makes a sharp distinction between the responses to God’s revelation made by:
(a) man in his original condition, i.e., Adam before the Fall;
(b) mankind, whose “understanding is subjected to blindness and the heart to depravity” (Inst. II.i.9)
(c) those that are “taught of Christ” through Scripture and whose eyes have been opened by the Holy Spirit.
– Cornelius Van Til, The Reformed Pastor and the Defense of Christianity & My Credo p.24