If man does not own the authority of Christ in the field of science, he assumes his own ultimate authority as back of his effort. The argument between the covenant-keeper and the covenant-breaker is never exclusively about any particular fact or about any number of facts. It is always, at the same time, about the nature of facts. And back of the argument about the nature of facts, there is the argument about the nature of man. However restricted the debate between the believer and the non-believer may be at any one time, there are always two world views ultimately at odds with one another. On the one side is a man who regards himself as being unable to find an intelligible interpretation of experience without reference to God as his Creator and to Christ as his Redeemer. On the other side is the man who is certain that he cannot find any such an interpretation. He assumes that there resides with him the power to make a universal negative statement about the nature of all reality.
The scientist who is a Christian therefore has the task of pointing out to his friend and colleague, who is not a Christian, that unless he is willing to stand upon the Christian story with respect to the world which has been redeemed through Christ, there is nothing but failure for him. Scientific effort is utterly unintelligible unless it is frankly based upon the order placed in the universe of created facts by Christ the Redeemer.
– Cornelius Van Til, The Protestant Doctrine of Scripture